Wintrobe's Atlas of Clinical Hematology

by Tkachuk, Douglas C.; Hirschmann, Jan V.

• ISBN13: 9780781770231
• ISBN10: 0781770238
• Edition: 1st
• Format: Hardcover
• Copyright: 2006-11-23
• Publisher: LWW

Summary

Featuring over 400 brilliantly sharp, high-resolution diagnostic digital photomicrographs combined with concise, clinically oriented text, this full-color atlas is a comprehensive pictorial guide to diagnostic hematology. Tied to the classic and world-renowned textbook Wintrobe's Clinical Hematology, this brand-new atlas enables physicians to see and readily comprehend diseased tissues and understand the complex assays routinely used in the care of patients with hematologic diseases. The comprehensive pictorial collection includes relevant clinical and radiological images accompanied by photomicrographs (surgical and autopsy specimens), and advanced diagnostic laboratory images that include molecular assays, FISH, and cytogenetics. All the major diseases in Wintrobe's and all the major hematolymphoid disorders recognized by the World Health Organization are included in this comprehensive collection of diagnostic images. The color pictures are combined with diagrams and tables that help readers use "algorithmic" approaches to diagnosis. Two complementary formats allow readers to approach hematologic diseases from either the classical disease categorization perspective of the Wintrobe text, or by an image-directed approach based on morphological pattern recognition in diseased tissues. A bound-in DVD contains large high-resolution photomicrographs that have been digitally enhanced to allow readers to interact with components of the print image.

Table of Contents

Preface	ix
Foreword	xi
Acknowledgments	xiii
Contributing Authors	xv
Anemia	1	(47)
David Barth
Jan V. Hirschmann
Microcytic Anemias	9	(12)
Iron Deficiency	10	(4)
Thalassemia	14	(5)
Sideroblastic	19	(2)
Normocytic Anemias	21	(19)
Thalassemia	22	(5)
Hemolytic	27	(13)
Macrocytic Anemias	40	(8)
Acute Leukemias	48	(46)
Douglas C. Tkachuk
Jan V. Hirschmann
Clinical Findings	55	(6)
AML Blast Morphology	61	(3)
AML Subtypes	64	(22)
AML, Minimally Differentiated	64	(1)
AML, without Maturation	65	(1)
AML, with Maturation	65	(1)
Acute Myelomonocytic Leukemia	66	(2)
Acute Monoblastic/Monocytic Leukemias	68	(5)
Acute Erythroid Leukemia	73	(3)
Acute Megakaryoblastic Leukemia	76	(1)
AML with t(8;21)	77	(2)
Acute Promyelocytic Leukemia	79	(4)
AML with inv16	83	(2)
AML with 11 q23 Abnormalities	85	(1)
AML with Multilineage Dysplasia	86	(1)
Chloromas	86	(2)
Rare AML Subtypes	88	(1)
AML Mimics	89	(2)
Precursor Lymphoblastic Leukemias	91	(3)
Myelodysplastic Syndromes	94	(11)
Douglas C. Tkachuk
Kathy Chun
Jan V.Hirschmann
Peripheral Blood	98	(1)
Aspirate Smear	99	(3)
Biopsy	102	(2)
Cytogenetics	104	(1)
Chronic Myeloproliferative Syndromes	105	(32)
Tracy I. George
Clinical Presentation	111	(5)
Chronic Myelogenous Leukemia	116	(7)
Polycythemia Vera	123	(3)
Chronic Idiopathic Myelofibrosis	126	(3)
Essential Thrombocythemia	129	(2)
Chronic Neutrophilic Leukemia	131	(1)
Chronic Eosinophilic Leukemia	131	(1)
Systemic Mastocytosis	132	(2)
Chronic Myelomonocytic Leukemia	134	(1)
Atypical Chronic Myelogenous Leukemia	135	(1)
Juvenile Myelomonocytic Leukemia	136	(1)
Lymphoproliferative Disorders	137	(75)
Jan V. Hirschmann
Denis J. Bailey
Douglas C. Tkachuk
Mature B-Cell Disorders	154	(40)
Chronic Lymphocytic Leukemia/Lymphoma	154	(5)
B-Cell Prolymphocytic Leukemia	159	(1)
Lymphoplasmacytic Lymphoma	160	(1)
Hairy Cell Leukemia	161	(2)
Multiple Myeloma	163	(6)
Splenic Marginal Zone Lymphoma	169	(1)
Extranodal MALT Lymphoma	170	(4)
Follicular Lymphoma	174	(7)
Mantle Cell Lymphoma	181	(2)
Diffuse Large B-Cell Lymphoma	183	(8)
Burkitt Lymphoma/Leukemia	191	(3)
T-Cell Lymphoproliferative Disorders	194	(12)
Adult T-Cell Leukemia/Lymphoma	194	(1)
Extranodal NK/T-Cell Lymphoma	195	(1)
Hepatosplenic T-Cell Lymphoma	196	(1)
Mycosis Fungoides and Sezary Syndrome	197	(2)
Peripheral T-Cell Lymphoma	199	(1)
Angioimmunoblastic T-Cell Lymphoma	200	(2)
Precursor T-Lymphoblastic Leukemia/Lymphoma	202	(1)
Anaplastic CD30+ Large Cell Lymphoma	203	(3)
Hodgkin Lymphoma	206	(6)
Flow Cytometry in the Diagnosis of Hematopoietic Diseases	212	(30)
Steven J. Kussick
Myeloid Disorders	228	(4)
B-Cell Disorders	232	(5)
T-Cell and NK Disorders	237	(5)
Cytology and Laser Scanning Cytometry	242	(33)
William R. Geddie
Techniques	249	(5)
Benign Hematolymphoid Disorders	254	(3)
B-Cell Disorders	257	(11)
T-Cell Disorders	268	(4)
Hodgkin Lymphoma	272	(1)
Metastatic Lymph Node Lesions	273	(2)
Approach to the Microscopic Evaluation of Blood and Bone Marrow	275	(54)
Douglas C. Tkachuk
Jan V. Hirschmann
Peripheral Blood Film	280	(14)
Red Blood Cells	282	(3)
Lymphoid Cells	285	(5)
Granulocytes	290	(4)
Bone Marrow	294	(35)
Aspirate Smears	295	(14)
Biopsy	309	(16)
Clot Section	325	(2)
Touch (Imprint) Prep	327	(2)
Index	329