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9780126289305

Xenobiotics and Inflammation : Roles of Cytokines and Growth Factors

by ;
  • ISBN13:

    9780126289305

  • ISBN10:

    0126289301

  • Format: Hardcover
  • Copyright: 1994-06-01
  • Publisher: Academic Pr

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Supplemental Materials

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Summary

The affect of xenobiotics on host resistance in general and specific immune functions has become the focus of much current research. This book synthesises current information on how chemicals (xenobiotics) can affect the immune system to cuse dysfunction, focusing on the process of inflammation. It provides a much needed, single-source reference for researchers investigation the mechanisms responsible for altered host resistance following exposture to xenobiotics. Emphasis is placed on the roles of cytokines and growth factors in the inflammatory process and how such processes are altered and modulated by xenobiotics. This volume contains information pertinent to those exploring cell growth, angiogenesis, hematopoetic differentiation, and recruitment to and proliferation of cells in various tissue sites. This volume brings together experts in inflammation, cytokines, cell growth, immunology and toxicology to provide a highly yseful volume modulated by chemicals. Divided into three sections, the book offers an organ system approach to understanding inflammation and xenobiotics.

Table of Contents

Foreword
Immunotoxicity and Inflammation: An Overview
The Inflammatory Process
Inflammatory Cytokines
Induction of Inflammation: Cytokines and Acute Phase Proteins
Eole of Tumor Necrosis Factor-Alpha in Acute and Chronic Inflammatory Responses: Novel Therapeutic Approaches
Bone Marrow Phagocytes, Inflammatory Medicators and Benzene Toxicity
Nitrosamine-Induced Inflammation: Induction of Cytokines Affecting Macrophage Differentiation and Function
The Effects of Metals on Immune System Development and Function
Xenobiotic-Induced Skin Inflammation
The Pathogenesis of Atherosclerosis: A Cytokine Hypothesis
Ozone-Induced Inflammatory Response in Pulmonary Cells
Pulmonary Fibrosis Induced By Bleomycin and Fibers
Role of Inflammatory Mediators and Cytokines in Endotoxin-Induced Hepatotoxicity
CNS: Viral Infection and Immune-Mediated Inflammation
Subject Index
Table of Contents provided by Publisher. All Rights Reserved.

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