The Year in Diabetes and Obesity, Volume 1212

by Powers, Alvin C.; Ahima, Rexford S.

• ISBN13: 9781573317566
• ISBN10: 157331756X
• Edition: 1st
• Format: Paperback
• Copyright: 2010-12-20
• Publisher: Wiley-Blackwell

Summary

The Year in Diabetes and Obesity will fulfill a critical need in by publishing timely, thought-provoking reviews on the molecular, basic, and clinical aspects of diabetes and obesity. Reviews in the inaugural issue will include: Early life nutrition and Metabolic Programming; Neuroendocrine Responses to Hypoglycemia; Cardiovascular Outcomes in Type 2 Diabetes: The Impact of Preventative Therapies; Gastrointestinal Hormones and beta-cell Mass Regulation; CNS leptin and Insulin Action in the Control of Energy Homeostasis; The Genetics of Type 2 Diabetes: What have we learned from GWAS?; Management of Hyperglycemia in Hospitalized Patients; Circadian control of metabolism; Metabolic surgery for type 2 diabetes; and Adipokines.NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit http://ordering.onlinelibrary.wiley.com/subs.asp?ref=1749-6632&doi=10.1111/(ISSN)1749-6632.ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order ( www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.

Author Biography

Alvin C. Powers, M.D. is the Joe C. Davis Chair in Biomedical Science Professor, Medicine, and Molecular Physiology and Biophysics. Director, Vanderbilt Diabetes Center. Director, Division of Diabetes and Endocrinology.

Dr. Powers is a physician-scientist whose research on type 1 and type 2 diabetes focuses on pancreatic islet biology, development, and function. His research is or has been supported by the NIH, the VA Research Service, the JDRF, and the American Diabetes Association (ADA). Dr. Powers is also the Director of the Vanderbilt Medical Student Research Training Program in Diabetes, Endocrinology, and Metabolism and the Coordinator for the NIDDK Medical Student Research Program in Diabetes.

Table of Contents

Pathogenesis of type 1 diabetes: lessons from natural studies ofhigh-risk individuals 1
Natalie Nokoff and Marian Rewers

The role of reactive oxygen species and proinflammatorycytokines in type 1 diabetes pathogenesis 16
Lindsey E. Padgett, Katarzyna, A. Broniowska, Polly A. Hansen,John A. Corbett and Hubert M. Tse

Cardiovascular disease and glycemic control in type 2 diabetes:now that the dust is settling from large clinical trials 36
Francesco Giorgino, Anna Leonardini and Luigi Laviola

Type 2 diabetes in South Asians: similarities and differenceswith white Caucasian and other populations 51
Unjali P. Guyral, R. Pradeepa, Mary Beth Weber, K.M. VenkatNarayan and V. Mohan

Type 2 diabetes in East Asians: similarities and differenceswith population in Europe and the United States 64
Ronald C.W. Ma and Juliana C.N. Chan

Islet β cell mass in diabetes and how it relates tofunction, birth, and death 92
Gordon C. Weir and Susan Bonner-Weir

Nanoalcoholic fatty liver disease: an emerging threat to obeseand diabetic individuals 106
Howard C. Masuoka and Naga Chalasani

What is metabolic syndrome, and why are children getting it23
Ram Weiss, Andrew A. Bremer and Robert H. Lustig

Physical activity in obesity and metabolic syndrome 141
Barbara Strasser

Human adipose dynamics and metabolic health 160
Bin Feng, Tracy Zhang and Haiyan Xu

The genetics of human obesity 178
Qianghua Xia and Struan F.A. Grant

Managing obesity in primary care practice: a narrative review191
Raymond Carvajal, Thomas A. Wadden, Adam G. Tsai, KatherinePeck and Caroline H. Moran