Cancer Stem Cells (CSCs): Similarities and Variation of the Theme of Normal Stem Cells | |
Introduction | |
Stem cells in the life of an organism | |
Cancer Stem Cells (CSCs) | |
Self-renewal and differentiation in CSCs | |
CSC plasticity as regulated by intrinsic and extrinsic factors | |
Future Perspectives | |
Abbreviations | |
References | |
Leukemic Stem Cells | |
Introduction | |
Dysregulation of hematopoiesis in leukemia | |
Identification and isolation of Cancer Initiating Cell(s) in Leukemia | |
Molecular regulation of the aberrant hierarchies | |
Future Perspectives | |
Abbreviations | |
References | |
Isolation and Characterization of Breast and Brain Cancer Stem Cells | |
Introduction | |
Breast cancer Stem Cells | |
Brain Cancer Stem Cells | |
Conclusion | |
Abbreviations | |
References | |
Cancer Stem Cell Side Populations | |
Introduction | |
Stem cell side populations (SP) | |
SP in normal tissues | |
SP in tumors | |
Overcoming SP limitations | |
Conclusion and future perspectives | |
Abbreviations | |
References | |
Evidence for Cancer Stem Cells in Retinoblastoma | |
Introduction | |
Elusive Origins of Retinoblastoma | |
Sources of Retinoblastoma cells for study | |
Precedent for cancer stem cells | |
Side populations in Retinoblastoma | |
Immunoreactivity to stem cell markers in Retinoblastoma | |
Conclusion | |
Abbreviations | |
References | |
Ovarian Stem Cell Biology and the Emergence of Ovarian Cancer Stem Cells | |
Introduction | |
Human ovary: An overview | |
Stem Progenitor Cells Exist In the Adult Mammalian Ovary | |
Is ovarian cancer a stem cell disease? | |
Abbreviations | |
References | |
Prostate Cancer Stem Cells | |
Introduction | |
The human prostate: biology, gland architecture and pathological alterations | |
Prostate epithelial stem cells | |
Prostate cancer stem cells | |
Stem cell tracking in the prostate | |
Conclusions and future directions | |
Abbreviations | |
References | |
Molecular Signatures of Highly Malignant Melanoma Stem Cells | |
General Properties of Human Melanomas | |
Characteristics of Stem Cell-derived Melanomas | |
The Cat Model System for Stem Cell Melanomas | |
Challenges of Research in Cancer Stem Cells and Therapeutics | |
Summary and Conclusions | |
Abbreviations | |
References | |
Invasion Program of Normal and Cancer Stem Cells | |
Introduction | |
The basics of tumor progression: invasion and metastasis | |
Epithelial to mesenchymal transitions in development and its relation to the invasive process | |
Regulation of EMT: from signals to molecular pathways | |
EMT and cancer stem cells | |
Can stem cell properties be extensive to invasive tumor cells? | |
Is there a unique EMT program linked to invasion? | |
Evidences of EMT in human clinical tumors | |
Expression of mesenchymal markers and cadherin switching in carcinomas | |
Expression of EMT inducers in human tumors | |
EMT may occur in a specific subset of breast carcinomas | |
Conclusions and perspectives | |
Abbre | |
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