Functional MRI An Introduction to Methods

by Jezzard, Peter; Matthews, Paul M.; Smith, Stephen M.

• ISBN13: 9780192630711
• ISBN10: 0192630717
• Format: Hardcover
• Copyright: 2001-12-27
• Publisher: Oxford University Press

Summary

This book provides a comprehensive introduction to functional magnetic resonance imaging (fMRI), the scanning technique which allows the mapping of active processes within the brain.There are six sections to the book with chapters from an expert international team. Part I provides a broad overview of the field and sets the context. Part II describes the physiological and physical background to fMRI, including coverage of the hardware required and pulse sequence selection.Practical issues involving experimental design of the paradigms, psycho-physical stimulus delivery and subject response are covered in Part III, followed by a comprehensive treatment of data analysis in Part IV. Part V deals with practical applications of the technique in the field of neuroscienceand in clinical practice. The final section describes how fMRI can be integrated with other neuro-electromagnetic functional mapping techniques.Functional Magnetic Resonance Imaging: An Introduction to Methods is written to be accessible to a wide-ranging audience of research scientists interested in studying how the normal brain works, and clinicians interested in monitoring disease states and processes.

Table of Contents

List of contributors	ix
Abbreviations	xi
I INTRODUCTION	1	(34)
An introduction to functional magnetic resonance imaging of the brain	3	(32)
Paul M. Matthews
II PHYSICS AND PHYSIOLOGY	35	(140)
Brain energy metabolism and the physiological basis of the haemodynamic response	37	(30)
Albert Gjedde
Principles of nuclear magnetic resonance and MRI	67	(26)
Peter Jezzard
Stuart Clare
Ultra-fast MRI	93	(16)
Richard A. Jones
Jason A. Brookes
Chrit T.W. Moonen
Hardware for functional MRI	109	(14)
Gary H. Glover
Selection of the optimal pulse sequence for functional MRI	123	(22)
Peter A. Bandettini
Spatial and temporal resolution in fMRI	145	(14)
Ravi S. Menon
Bradley G. Goodyear
Quantitative measurement using fMRI	159	(16)
Richard D. Hoge
G. Bruce Pike
III EXPERIMENTAL DESIGN	175	(38)
Effective paradigm design	177	(20)
David I. Donaldson
Randy L. Buckner
The scanner as a psychophysical laboratory	197	(16)
Robert Savoy
IV ANALYSIS OF FUNCTIONAL IMAGING DATA	213	(96)
Overview of fMRI analysis	215	(14)
Stephen M. Smith
Preparing fMRI data for statistical analysis	229	(14)
Stephen M. Smith
Head motion and its correction	243	(8)
Mick J. Brammer
Statistical analysis of activation images	251	(20)
Keith J. Worsley
Registration, brain atlases and cortical flattening	271	(24)
Mark Jenkinson
Extracting brain connectivity	295	(14)
Christian Buchel
Karl Friston
V fMRI APPLICATIONS	309	(42)
fMRI: applications in cognitive neuroscience	311	(18)
Adrian M. Owen
Russel Epstein
Ingrid S. Johnsrude
Clinical applications of mapping neurocognitive processes in the human brain with functional MRI	329	(22)
Keith R. Thulborn
Antonio Gisbert
VI INTEGRATING TECHNOLOGIES	351	(32)
Dynamic functional neuroimaging integrating multiple modalities	353	(30)
John S. George
David M. Schmidt
David M. Rector
Chris Wood
Index	383