Immunology at a Glance

by Playfair, J. H. L.; Chain, B. M.

• ISBN13: 9780632054060
• ISBN10: 0632054069
• Edition: 7th
• Format: Paperback
• Copyright: 2001-01-01
• Publisher: John Wiley & Sons Inc

Summary

Immunology at a Glance is designed to be a concise, readily accessible introduction and revision aid for undergraduate medical and science students. Following the now familiar, easy-to-use format, each topic is presented as a double-page spread with key facts accompanied by clear, informative line diagrams illustrating the essential points. The seventh edition of this popular immunology textbook has been completely updated to ensure that core knowledge about immunology is summarized in the 'at a glance' format. Immunology At A Glance will continue to appeal to all students of biomedical science and medicine who want a quick, yet thorough grasp of immunology. Condenses the subject into 41 double-page spreads, each corresponding roughly to a 50 minute lecture. Presents a schematic diagram on the left page and a concise explanation on the right showing the mechanisms involved in immunological processes. Has been completely updated with particular emphasis on recent understanding of the genetic basis of immune responses Immunology at a Glance will continue to appeal to all students of biomedical science and medicine who want a quick, yet thorough, grasp of immunology.

Table of Contents

Preface	p. 6
Acknowledgements	p. 6
Note on the seventh edition	p. 6
How to use this book	p. 7
Further reading	p. 7
Immunity
The scope of immunology	p. 8
Natural and adaptive immune mechanisms	p. 10
Evolution of immune mechanisms	p. 12
Cells involved in immunity: the haemopoietic system	p. 14
Natural immunity
Complement	p. 16
Acute inflammation	p. 18
Phagocytic cells: the reticulo-endothelial system	p. 20
Phagocytosis	p. 22
Adaptive immunity
The cellular basis
Lymphocytes	p. 24
Primary lymphoid organs and lymphopoiesis	p. 26
Secondary lymphoid organs and lymphocyte traffic	p. 28
The molecular basis
Evolution of recognition molecules--the immunoglobulin superfamily	p. 30
The major histocompatibility complex	p. 32
The T cell receptor	p. 34
Antibody diversification and synthesis	p. 36
Antibody structure and function	p. 38
The adaptive immune response
Antigen recognition and processing	p. 40
The antibody response	p. 42
Antigen-antibody interaction and immune complexes	p. 44
Cell-mediated immune responses	p. 46
Regulation
Tolerance	p. 48
Idiotypes, anti-idiotypes and networks	p. 50
The cytokine network	p. 52
Immunity, hormones and the brain	p. 54
Potentially useful immunity
Anti-microbial immunity: a general scheme	p. 56
Immunity to viruses	p. 58
Immunity to bacteria	p. 60
Immunity to fungi	p. 62
Immunity to protozoa	p. 64
Immunity to worms	p. 66
Immunity to tumours	p. 68
Undesirable effects of immunity
Harmful immunity: a general scheme	p. 70
Allergy and anaphylaxis	p. 72
Immune complexes, complement and disease	p. 74
Chronic and cell-mediated inflammation	p. 76
Autoimmunity	p. 78
Transplant rejection	p. 80
Altered immunity
Immunosuppression	p. 82
Immunodeficiency	p. 84
HIV and AIDS	p. 86
Immunostimulation and vaccination	p. 88
Appendices
Comparative sizes	p. 90
Comparative molecular weights	p. 90
Landmarks in the history of immunology	p. 91
Some unsolved problems	p. 91
The CD classification	p. 92
Index	p. 94
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