Knowledge Discovery in Bioinformatics Techniques, Methods, and Applications

by Hu, Xiaohua; Pan, Yi

• ISBN13: 9780471777960
• ISBN10: 047177796X
• Edition: 1st
• Format: Hardcover
• Copyright: 2007-06-22
• Publisher: Wiley-Interscience

Summary

The purpose of this edited book is to bring together the ideas and findings of data mining researchers and bioinformaticians by discussing cutting-edge research topics such as, gene expressions, protein/RNA structure prediction, phylogenetics, sequence and structural motifs, genomics and proteomics, gene findings, drug design, RNAi and microRNA analysis, text mining in bioinformatics, modelling of biochemical pathways, biomedical ontologies, system biology and pathways, and biological database management.

Author Biography

Xiaohua Hu, PhD, is Assistant Professor of Computer Science in the College of Information Science and Technology at Drexel University. His research has been published in such journals as IEEE Computer, Knowledge and Information Systems, Journal of Intelligent Systems, and the International Journal of Applied Intelligence.

Yi Pan, PhD, is Chair and Professor of Computer Science at Georgia State University. His pioneering work in computing using reconfigurable optical buses has been cited by researchers around the world. Dr. Pan is co-holder of three United States patents (pending) and five provisional patents.

Table of Contents

Current methods for protein secondary-structure prediction based on support vector machines	p. 1
Comparison of seven methods for mining hidden links	p. 27
Voting scheme-based evolutionary kernel machines for drug activity comparisons	p. 45
Bioinformatics analyses of Arabidopsis thaliana tiling array expression data	p. 57
Identification of marker genes from high-dimensional microarray data for cancer classification	p. 71
Patient survival prediction from gene expression data	p. 89
RNA interference and microRNA	p. 113
Protein structure prediction using string kernels	p. 145
Public genomic databases : data representation, storage, and access	p. 169
Automatic query expansion with keyphrases and POS phrase categorization for effective biomedical text mining	p. 197
Evolutionary dynamics of protein-protein interactions	p. 209
On comparing and visualizing RNA secondary structures	p. 233
Integrative analysis of yeast protein translation networks	p. 251
Identification of transmembrane proteins using variants of the self-organizing feature map algorithm	p. 267
TriCluster : mining coherent clusters in three-dimensional microarray data	p. 295
Clustering methods in a protein-protein interaction network	p. 319
Table of Contents provided by Blackwell. All Rights Reserved.