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9780471777960

Knowledge Discovery in Bioinformatics Techniques, Methods, and Applications

by ;
  • ISBN13:

    9780471777960

  • ISBN10:

    047177796X

  • Edition: 1st
  • Format: Hardcover
  • Copyright: 2007-06-22
  • Publisher: Wiley-Interscience

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Summary

The purpose of this edited book is to bring together the ideas and findings of data mining researchers and bioinformaticians by discussing cutting-edge research topics such as, gene expressions, protein/RNA structure prediction, phylogenetics, sequence and structural motifs, genomics and proteomics, gene findings, drug design, RNAi and microRNA analysis, text mining in bioinformatics, modelling of biochemical pathways, biomedical ontologies, system biology and pathways, and biological database management.

Author Biography

Xiaohua Hu, PhD, is Assistant Professor of Computer Science in the College of Information Science and Technology at Drexel University. His research has been published in such journals as IEEE Computer, Knowledge and Information Systems, Journal of Intelligent Systems, and the International Journal of Applied Intelligence.

Yi Pan, PhD, is Chair and Professor of Computer Science at Georgia State University. His pioneering work in computing using reconfigurable optical buses has been cited by researchers around the world. Dr. Pan is co-holder of three United States patents (pending) and five provisional patents.

Table of Contents

Current methods for protein secondary-structure prediction based on support vector machinesp. 1
Comparison of seven methods for mining hidden linksp. 27
Voting scheme-based evolutionary kernel machines for drug activity comparisonsp. 45
Bioinformatics analyses of Arabidopsis thaliana tiling array expression datap. 57
Identification of marker genes from high-dimensional microarray data for cancer classificationp. 71
Patient survival prediction from gene expression datap. 89
RNA interference and microRNAp. 113
Protein structure prediction using string kernelsp. 145
Public genomic databases : data representation, storage, and accessp. 169
Automatic query expansion with keyphrases and POS phrase categorization for effective biomedical text miningp. 197
Evolutionary dynamics of protein-protein interactionsp. 209
On comparing and visualizing RNA secondary structuresp. 233
Integrative analysis of yeast protein translation networksp. 251
Identification of transmembrane proteins using variants of the self-organizing feature map algorithmp. 267
TriCluster : mining coherent clusters in three-dimensional microarray datap. 295
Clustering methods in a protein-protein interaction networkp. 319
Table of Contents provided by Blackwell. All Rights Reserved.

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