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9781860943270

Prostate Cancer: Clinical and Scientific Aspects Bridging the Gap

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  • ISBN13:

    9781860943270

  • ISBN10:

    1860943276

  • Edition: 1st
  • Format: Hardcover
  • Copyright: 2004-02-01
  • Publisher: IMPERIAL COLLEGE PRESS
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Summary

(Imperial College Press) Imperial College, London, UK. Aimed to bridge the gap between clinicians and scientists, text provides the latest in the field of prostate cancer. Presents translational research for improving the diagnosis and treatment of prostate cancer. Covers epidemiology, pathology, molecular biology, prevention, and clinical management.

Table of Contents

Forewordp. xi
Prefacep. xiii
Prostate Cancer: Bridging the Gap
Prostate Cancer--Some Clinical and Scientific Dilemmasp. 3
Prostate Cancer: Epidemiology and Genetics
The Epidemiology of Prostate Cancerp. 23
Genetic Aberrations in Prostate Tumoursp. 35
Prostate Gland: Development, Differentiation and Pathology (in Relationship to Malignancy)
Development and Differentiation of the Prostate Glandp. 71
Growth Factors in Prostatic Developmentp. 91
The Prostate and Cancer: An Introduction to Normal Morphology and Histopathology for Research Scientistsp. 111
Molecular and Cell Biology of Prostate Cancer
Cell Lines as Models of Prostate Cancerp. 143
Animal Models of Prostate Cancerp. 227
Transgenic Mouse Models of Prostate Carcinoma: Anatomic, Histopathologic, and Molecular Considerationsp. 245
Androgen Regulated Gene Expression and Mutation of the Androgen Receptorp. 321
Ion Channels in Prostate Cancerp. 339
MHC Expression and Immune Mechanisms in Prostate Cancerp. 359
Growth Factors in Prostate Cancerp. 399
Epithelial-Mesenchymal Interactions in Prostate Cancerp. 421
Cell Adhesion Molecules in Genitourinary Cancerp. 455
Matrix Metalloproteinases as Potential Targets for Prostate Cancer Therapyp. 473
Role of the Bone Morphogenetic Protein Family and Their Receptors in Prostate Cancer Progressionp. 493
Apoptosis and Cell Cycle Deregulation in Prostate Cancerp. 511
Oncogenes and Tumour Suppressor Genes in Prostate Cancerp. 551
Bcl-2 Family Proteins and Prostate Cancer Progression: Potential for Therapeutic Interventionsp. 595
Emerging Technologies and New Strategies in Prostate Cancer Researchp. 619
New Perspectives in Prevention, Control and Clinical Management of Prostate Cancer
An Analysis of Methodology in Clinical Studies of Prostate Cancer: Misled and Misinterpretedp. 649
Prevention of Prostate Cancerp. 667
Screening for Prostate Cancerp. 683
Prognostic Markers in Prostate Cancer: Clinical Valuep. 709
Detection and Diagnosis of Prostate Cancer: The Role of PSAp. 769
The Molecular Staging of Prostate Cancerp. 793
The Clinical Management of Prostate Cancer--The Surgeon's Approach and Outcomesp. 811
The Clinical Management of Prostate Cancer--The Medical Oncologist's Approach and Outcomesp. 833
The Clinical Management of Prostate Cancer--The Radiation Oncologist's Approach and Outcomesp. 853
The Care of Patients with Advanced Hormone Relapsed Prostate Cancerp. 911
The Biology and Treatment of Bone Metastases in Prostate Cancerp. 931
Prostate Cancer Gene Therapyp. 957
Psychosocial Aspects of Prostate Cancerp. 1011
Psychosocial Support of the Prostate Cancer Patientp. 1039
Controversies in the Management Choices for the Treatment of Prostate Cancer: A Personal View as Surgeonsp. 1097
The Problems of Prostate Cancer in Developing Countries--An African Perspectivep. 1123
Prostate Cancer in South Central Asia: A Perspective from the Developing Worldp. 1131
About the Authorsp. 1187
Indexp. 1219
Table of Contents provided by Rittenhouse. All Rights Reserved.

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