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9780470755037

Cough: Causes, Mechanisms and Therapy

by ; ;
  • ISBN13:

    9780470755037

  • ISBN10:

    0470755032

  • Format: eBook
  • Copyright: 2008-04-01
  • Publisher: Wiley-Blackwell
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Summary

Cough is the most familiar symptom of respiratory disease, and a problem which general practitioners must deal with on a daily basis. This timely volume draws together a wealth of recent research into the mechanisms, pharmacology and therapies for cough, and places these in clinical context. The text incorporates guidelines on the most common causes of cough, discusses treatments and pitfalls in management, summarizes current research on physiology, pharmacology and treatment of cough, and gives practical advice on diagnosis and management issues for the clinician.Cough: Causes, Mechanisms and Therapy is the most comprehensive, up-to-date account of the subject. It will update clinical and basic medical scientists, and promote future research. Readers are encouraged to implement the clinical implications of the discussion into routine practice. This volume will appeal to all those involved in the treatment of respiratory disease, particularly those in hospital respiratory units, and will also be of use to interested general practitioners.

Table of Contents

Contributors
Preface
Introduction
The clinical and pathophysiological challenge of cough
Epidemiology of cough
A brief overview of the mechanisms of cough
Cough in the clinic
Clinical assessment of cough
Measurement and assessment of cough
Cough sensitivity: the use of provocation tests
Causes, assessment and measurement of cough in children
The quality of life in coughers Section 3: Clinical conditions with cough
Cough in lower airway infections
Cough in gastro-oesophageal reflux
Cough in postnasal drip, rhinitis and rhinosinusitis
Cough and airway hyperresponsiveness
Cough in chronic obstructive pulmonary disease (COPD)
Cough in suppurative airway diseases
Cough in cancer patients
Pathophysiology
Sensory pathways for the cough reflex
Neurogenesis of cough
Plasticity of vagal afferent fibres mediating cough
Motor mechanisms and the mechanics of cough
Mucus hypersecretion and mucus clearance in cough
Animal models of cough
Therapy
Mechanisms of actions of centrally acting antitussives - electrophysiological and neurochemical analysis
Pharmacology of peripherally acting antitussives
Current and potential future antitussive therapies
Placebo effects of antitussive treatments on cough associated with acute upper respiratory tract infection
Mucoactive agents for the treatment of cough
Management of cough
Index
Table of Contents provided by Publisher. All Rights Reserved.

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