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9780470745021

Advanced Techniques in Diagnostic Cellular Pathology

by ;
  • ISBN13:

    9780470745021

  • ISBN10:

    0470745029

  • Format: eBook
  • Copyright: 2009-03-01
  • Publisher: Wiley
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Summary

There is an increasing need for an understanding of the scientific basis of cellular pathology to facilitate a growing trend towards inter-disciplinary understanding in biomedical sciences. Advanced Techniques in Diagnostic Cellular Pathology provides biomedical science students and professionals with the necessary background information, principles and methodology of advanced techniques to assist diagnosis in the modern cellular pathology laboratory.Each chapter is carefully structured to introduce the very latest techniques and describe their clinical purpose, principle, method and application in cellular pathology. The advantages of various methods for preparing, observing and demonstrating cells and tissues employed to assist in diagnosis are explored, in addition to the use of quantitative methods in the detection and diagnosis of disease. An accompanying web site presents full colour digital images of microscope slides, advanced protocols that the book can reference, appendices and web links.This book is invaluable for newly qualified postgraduates needing to get up to speed on a broad range of analytical techniques. It is also of interest to professionals working in diagnostic, industrial and research laboratories for continual professional development and training.

Table of Contents

List of Contributors
Preface
List of Tables
List of Figures
Supplementary Materials
Virtual Microscopy
Introduction
Digital (virtual) microscopy: equipment for implementation
The virtual slide format
Image serving and viewing
Applications of virtual microscopy
Virtual microscopy in education
Computational aspects of virtual microscopy
Conclusions
Cytopathology
Introduction
Basic principles
Cytodiagnosis
Gynaecological cytopathology
Conclusions
Flow Cytometry
Introduction
Sample preparation
Principles of the flow cytometer
Clinical applications
The future for flow cytometry
Conclusions
Immunocytochemistry
Introduction
Basic principles
Clinical immunocytochemistry
Conclusions
Microarray-based Comparative Genomic Hybridization
Introduction
Principles of array CGH
aCGH platforms
Choosing the right platform
Analysis and validation
Finding the target
Data integration
Clinical applications
Conclusions
Tissue In SituHybridization
Introduction
ISH probes
Probe labels
ISH detection systems
Tissue preparation and the ISH procedure
Signal amplification
ISH controls
Clinical applications of tissue ISH
ISH automation
Image capture and analysis
Recent developments and future directions in tissue ISH
Conclusions
Index
Table of Contents provided by Publisher. All Rights Reserved.

Supplemental Materials

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