Brook's Clinical Pediatric Endocrinology, 5th Edition

This new edition of the benchmark text on clinical pediatric endocrinology still remains at the forefront of world clinical opinion. Furthermore, the style, which has been the hallmark of the book for the last 20 years, has been maintained for this Fifth Edition.New features of this Fifth Edition include: Special new chapters cover the fetal origins of adult disease and the endocrine consequences and management of critical illness Now opens with a basic science section summarizing the mechanisms of hormone action, genomics, proteomics and the application of molecular biology to clinical practice Two new co-editors have been introduced - Peter Clayton and Rosalind Brown Every chapter has been updated

Foreword. Preface to the fifth edition. Preface to the first edition. 1. Principles of hormone action. 2. Genetics, genomics, proteomics and bioinformatics. 3. Measuring hormones, molecular tests and their clinical application. 4. Congenital disorders of the hypothalamic-pituitary axis. 5. Normal and disordered growth. 6. Genetic syndrome and dysmorphology. 7. Acquired abnormalities of the hypothalamic-pituitary axis leading to growth impairment. 8. Development of the reproductive system. 9. Ambigous gentialia. 10. Normal and abnormal puberty. 11. Gynaecology. 12. The thyroid and its disorders. 13. The parathyroid and disorders of calcium meabolism. 14. Disorders of bone metabolism. 15. Adrenal cortex and it's disorders. 16. Polyglandular syndromes. 17. Disorders of water balance. 18. Endocrine programming and the fetal and early-life origins of adult disease. 19. Weight regulation and monogenic obesity. 20. Metabolic consequences of obesity and their manangement. 21. Diabetes mellitus. 22. Hypoglycemia. 23. Endocrine consequences of systemic disease: critical illness. 24. Consequences of radiotherapy, chemotherapy and bone marrow transplant. 25. Tests and normal value in pediatric endocrinology. Appendix. Index