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9780195108248

Cost-Effectiveness in Health and Medicine

by ; ; ;
  • ISBN13:

    9780195108248

  • ISBN10:

    0195108248

  • Format: Hardcover
  • Copyright: 1996-07-18
  • Publisher: Oxford University Press
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Supplemental Materials

What is included with this book?

Summary

A unique, in-depth discussion of the uses and conduct of cost-effectiveness analyses (CEAs) as decision-making aids in the health and medical fields, this volume is the product of over two years of comprehensive research and deliberation by a multi-disciplinary panel of economists, ethicists,psychometricians, and clinicians. Exploring cost-effectiveness in the context of societal decision-making for resource allocation purposes, this volume proposes that analysts include a "reference-case" analysis in all CEAs designed to inform resource allocation and puts forth the most explicit setof guidelines (together with their rationale) ever defined on the conduct of CEAs. Important theoretical and practical issues encountered in measuring costs and effectiveness, evaluating outcomes, discounting, and dealing with uncertainty are examined in separate chapters. Additional chapters onframing and reporting of CEAs elucidate the purpose of the analysis and the effective communication of its findings. Cost-Effectiveness in Health and Medicine differs from the available literature in several key aspects. Most importantly, it represents a consensus on standard methods--a featureintegral to a CEA, whose principal goal is to permit comparisons of the costs and health outcomes of alternative ways of improving health. The detailed level at which the discussion is offered is another major distinction of this book, since guidelines in journal literature and in CEA-related bookstend to be rather general--to the extent that the analyst is left with little guidance on specific matters. The focused overview of the theoretical background underlying areas of controversy and of methodological alternatives, and, finally, the accessible writing style make this volume a top choiceon the reading lists of analysts in medicine and public health who wish to improve practice and comparability of CEAs. The book will also appeal to decision-makers in government, managed care, and industry who wish to consider the uses and limitations of CEAs.

Table of Contents

List of Contributors
xv
Introduction xvii
Cost-Effectiveness Analysis as a Guide to Resource Allocation in Health: Roles and Limitations
3(22)
What Is the Appropriate Perspective?
5(2)
Defining Outcomes and Costs from the Societal Perspective
7(2)
CEA as an Aid to Decision Making
9(3)
Other Methods for Making Decisions in Health
12(1)
Results of CEA and Other Methods Compared
13(5)
Current and Potential Uses of CEA
18(3)
Conclusion
21(1)
Recommendations
21(4)
Theoretical Foundations of Cost-Effectiveness Analysis
25(29)
What is Cost-Effectiveness Analysis?
26(3)
Theoretical Foundations for Valuing Individual and Social Well-Being
29(7)
Theoretical Foundations for Valuing Costs in CEA
36(1)
Applications of Theory to Methodologic Controversies
37(13)
Conclusion
50(4)
Framing and Designing the Cost-Effectiveness Analysis
54(28)
Framing the Study
54(14)
Designing the Study
68(11)
Conclusion
79(1)
Recommendations
79(3)
Identifying and Valuing Outcomes
82(53)
The Outcomes of Interest in Cost-Effectiveness Analysis
83(6)
Combining Duration of Life with Health-Related Quality of Life
89(5)
Health Status Measures
94(2)
Why Value Health Outcomes?
96(2)
Whose Preferences Should Be Used in CEA?
98(8)
Preference Classification Systems
106(4)
Techniques for Valuing Health States
110(9)
Toward Consistency Across Studies: A National Catalogue of Weights
119(3)
Recommendations
122(2)
Appendix 4.1: Generic Preference-Based Measures for Use in CEA
124(11)
Assessing the Effectiveness of Health Interventions
135(41)
Definitions
137(4)
Sources of Data for Probability Estimates
141(10)
Modeling to Estimate Effectiveness in a CEA
151(12)
Calculation of Net Effectiveness
163(4)
Conclusion
167(1)
Recommendations
168(8)
Estimating Costs in Cost-Effectiveness Analysis
176(38)
A Graphic Illustration of Economic Consequences
176(2)
Types of Resource Costs
178(25)
Measurement and Valuation of Resources in Gross-Costing
203(5)
Conclusion
208(1)
Recommendations
209(5)
Time Preference
214(33)
Discounting Costs
216(3)
Discounting Health Consequences
219(11)
Choosing the Discount Rate for CEA
230(3)
Recommendations
233(14)
A Theoretical Model of Intertemporal Decision Making Regarding Health and Other Commodities
236(2)
A Two-Stage Procedure for Incorporating Individual and Societal Time Preferences
238(9)
Reflecting Uncertainty in Cost-Effectiveness Analysis
247(29)
Parameter Uncertainty
248(19)
Modeling Uncertainty
267(3)
Recommendations
270(6)
Reporting Cost-Effectiveness Studies and Results
276(28)
The Journal Report
277(19)
The Technical Report
296(3)
Disclosure
299(1)
Conclusion
300(1)
Recommendations
301(3)
Appendix A: Summary Recommendations 304(9)
Worked Examples
312(1)
Appendix B: Cost-Effectiveness of Strategies to Prevent Neural Tube Defects 313(36)
Appendix C: The Cost-Effectiveness of Dietary and Pharmacologic Therapy for Cholesterol Reduction in Adults 349(43)
Glossary 392(21)
Index 413

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