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9783764362829

Tetracyclines in Biology, Chemistry and Medicine

by ; ;
  • ISBN13:

    9783764362829

  • ISBN10:

    3764362820

  • Format: Hardcover
  • Copyright: 2002-01-01
  • Publisher: Birkhauser
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Supplemental Materials

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Summary

Paratek Pharmaceuticals, Boston, MA. Provides a current account of the non-antimicrobial properties of tetracyclines, covering general properties, their chemistry, biology, and microbiologic action. Also discusses the tetracycline gene regulation system, and more. Hardcover, softcover not yet available.

Table of Contents

List of contributors
vii
Foreword ix
Section I Chemistry, biology and microbiologic action of tetracyclines
Mark L. Nelson
The chemistry and cellular biology of the tetracyclines
3(62)
Mark L. Nelson
Proton and metal ion binding of tetracyclines
65(42)
Siegfried Schneider
Section II Tetracycline-dependent gene regulation: A versatile tool for all organisms
Wolfgang Hillen
Gene regulation by the tetracycline-inducible Tet repressor-operator system-molecular mechanisms at atomic resolution
107(18)
Winfried Hinrichs
Christiane Fenske
Regulation of gene expression in yeast and plants by tetracycline-dependent regulatory systems
125(14)
Elisabeth Pook
Tetracyclines in the control of gene expression in eukaryotes
139(20)
Manfred Gossen
Hermann Bujard
Tetracycline-regulated gene expression to study oncogenes in vivo
159(18)
Jeffrey E. Kudlow
Interactions of tetracyclines with RNA
177(22)
Christian Berens
Section III Use of tetracyclines as non-antimicrobial medicinal agents
Robert A. Greenwald
Biologic, non-antibiotic properties of semi-synthetic and chemically modified tetracyclines - a structured, annotated bibliography
199(20)
Robert A. Greenwald
Lorne M. Golub
Tetracycline consumption in prehistory
219(18)
George J. Armelagos
Kristi Kolbacher
Kristy Collins
Jennifer Cook
Maria Krafeld-Daugherty
Tetracycline treatment of periodontal disease: antimicrobial and non-antimicrobial mechanisms
237(30)
Maria Emanuel Ryan
Danielle M. Baker
Inhibition of matrix metalloproteinases (MMPs) by tetracyclines
267(16)
Roeland Hanemaaijer
Natascha van Lent
Timo Sorsa
Tuula Salo
Yrjo T. Konttinen
Jan Lindeman
Structure/function studies of doxycycline effects on matrix metalloproteinase activity and cartilage degeneration
283(12)
Gerald N. Smith Jr.
Karen A. Hasty
Regulation of inflammatory mediators by tetracyclines
295(16)
Mukundan G. Attur
Mandar N. Dave
Nirupama Mohandas
Indravadan R. Patel
Steven B. Abramson
Ashok R. Amin
Tetracyclines and autoimmunity
311(14)
Helena Marzo-Ortega
Roland M Strauss
Paul Emery
Tetracycline photodynamics
325(8)
Brad R. Zerler
Subject Index 333

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