Separation and Purification by... | Buy

Covering a range of topics, this volume presents crystallization of polymorphs and the problems encountered in the separation of chiral compounds by selective crystallization, as well as aspects of the crystallization of amino acids, proteins, and pharmaceuticals. The introductory section includes state-of-the-art research on secondary nucleation, the mechanism for crystallization of proteins, kinetics of impurity effect on growth, and crystal morphology prediction. Other topics include the use of high-pressure crystallization in industrial processes, precipitation cases for organic and inorganic compounds, precipitation processes by antisolvents, fast reaction precipitation, and isoelectric precipitation.

Preface

xi

BASIC STUDIES

2

(44)

1. Crystal Morphology Predictive Techniques To Characterize Crystal Habit: Application to Aspirin (C(9)H(8)O(4))

2

(16)

Paul Meenan

2. Mechanism of Crystal Growth of Protein: Differential Scanning Calorimetry of Thermolysin Crystal Suspension

18

(10)

H. Ooshima

S. Urabe

K. Igarashi

M. Azuma

J. Kato

3. Source of Nuclei in Contact Nucleation as Revealed by Crystallization of Isomorphous Alums

28

(8)

Manijeh M. Reyhani

Gordon M. Parkinson

4. A Kinetic Model for Unsteady-State Crystal Growth in the Presence of Impurity

36

(10)

N. Kubota

M. Yokota

L.A. Guzman

CRYSTALLIZATION OF OPTICAL ISOMERS AND POLYMORPHS

46

(90)

5. Concentration Change of L-SCMC [S-(Carboxymethyl)-L-cysteine] in a Supersaturated Solution of DL-SCMC with Suspended L-SCMC Seeds in a Batch Operation

46

(13)

Ken Toyokura

M. Kurotani

J. Fujinawa

6. Purity Drop in Optical Resolution of Racemic Mixtures

59

(14)

M. Matsuoka

7. Separation of L-Mandelic Acid from Asymmetric Mixtures by Means of High-Pressure Crystallization

73

(10)

N. Nishiguchi

M. Moritoki

T. Shinohara

Ken Toyokura

8. Morphological Change Mechanism of Alpha-L-Glutamic Acid with Inclusion of L-Phenylalanine

83

(9)

M. Kitamura

9. Growth Process and Morphological Change of Beta-Glutamic Acid in the Presence of L-Phenylalanine

92

(9)

M. Kitamura

Y. Sumi

10. Crystallization Behaviors of Alpha- and Beta-Quizalofop-ethyl Polymorphs in Homogeneous Nucleation

101

(10)

K. Miyake

O. Araki

M. Matsumura

11. Crystallization of Di-L-phenylalanine Sulfate Monohydrate from Fermentation Broth

111

(12)

Tetsuya Kawakita

12. Characterization of Aluminum Trihydroxide Crystals Precipitated from Caustic Solutions

123

(13)

Mei-yin Lee

Gordon M. Parkinson

Peter G. Smith

Frank J. Lincoln

Manijeh M. Reyhani

STUDIES RELATED TO INDUSTRIAL CRYSTALLIZERS AND PROCESSES

136

(52)

13. Features of the High-Pressure Crystallization Process in Industrial Use

136

(14)

M. Moritoki

N. Nishiguchi

S. Nishida

14. Semibatch Precipitation of a Metallized Dye Intermediate: Reaction and Precipitation Condition Effects on Particle Size and Filterability

150

(22)

Kostas E. Saranteas

Gregory D. Botsaris

15. Effects of Seeding on Start-up Operation of a Continuous Crystallizer

172

(16)

H. Takiyama

H. Yamauchi

M. Matsuoka

CRYSTALLIZATION OF PARTICULAR ORGANIC COMPOUNDS

188

(42)

16. Recent Studies on Recovery of Oilseed Protein by Precipitation

188

(22)

Matheo Raphael

Sohrab Rohani

Frank Sosulski

17. Secondary Crystallization of Paraffin Solidified on a Cooled Plane Surface

210

(10)

K. Onoe

T. Shibano

S. Uji

Ken Toyokura

18. Crystallization of a Fatty Acid Mixture Using Spray Evaporation of Highly Volatile Solvents

220

(10)

K. Maeda

H. Enomoto

K. Fukui

S. Hirota

CRYSTALLIZATION OF PARTICULAR INORGANIC COMPOUNDS

230

(61)

19. Crystallization of Sodium Chloride with Amines as Antisolvents

230

(12)

T.G. Zijlema

H. Oosterhof

G.J. Witkamp

G.M. van Rosmalen

20. Semibatch Gas Antisolvent Precipitation of Poly (2,6-dimethyl-1, 4-phenylene ether)

242

(12)

F.E. Wubbolts

R.E.A. Buijsse

O.S.L. Bruinsma

J. de Graauw

G.M. van Rosmalen

21. Reactive Crystallization of Magnesium Hydroxide

254

(13)

Hideki Tsuge

Kyoichi Okada

Toru Yano

Naoko Fukushi

Hiroko Akita

22. Phosphate Recovery by Reactive Crystallization of Magnesium Ammonium Phosphate: Application to Wastewater

267

(10)

Izumi Hirasawa

Hiroyuki Nakagawa

Osamu Yosikawa

Masanori Itoh

23. Inclusion of Selenium in Ferrite Crystals

277

(14)

Y. Taguchi

M. Ohizumi

K. Aoyama

K. Katoh

INDEXES

291

Author Index

291

(1)

Affiliation Index

292

(1)

Subject Index

292

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