Contributors | p. ix |
Preface | p. xiii |
Acknowledgements | p. xv |
Glossary | p. xvii |
Reference annotations | p. xxi |
Basic Science | |
Embryology and gross structure | p. 3 |
Cells in the pleural cavity | p. 17 |
Liquid and protein exchange | p. 35 |
Physiological effects of pleural air or fluid | p. 45 |
Pleural inflammation | p. 56 |
Cytokines in pleural diseases | p. 63 |
Pleural infections | p. 90 |
Pleural fibrosis | p. 96 |
Pleural reaction to mineral dust | p. 109 |
Genetics of malignant mesothelioma | p. 120 |
Pharmacokinetics | p. 131 |
Experimental models in pleural disease | p. 149 |
Experimental models of mesothelioma | p. 167 |
Clinical Science | |
Approach to the patient with a pleural effusion | p. 183 |
Pleural fluid analysis | p. 191 |
Diagnostic radiology | p. 210 |
Interventional radiology | p. 238 |
Pleural histology | p. 249 |
Pleural cytology, tumor markers and immunohistochemistry | p. 256 |
Effusions from cardiac diseases | p. 282 |
Effusions from vascular causes | p. 289 |
Effusions from malignancy | p. 297 |
Effusions from parapneumonic infection and empyema | p. 310 |
Effusions from tuberculosis | p. 329 |
Effusions from atypical infections | p. 345 |
Effusions in immunocompromised hosts | p. 357 |
Effusions from lymphatic disruptions | p. 362 |
Effusions from collagen vascular disease | p. 370 |
Effusions due to drugs | p. 382 |
Effusions after surgery | p. 394 |
Hepatic hydrothorax | p. 402 |
Pleural effusions due to gastrointestinal disease | p. 410 |
Pleural effusions due to obstetric and gynecological conditions | p. 419 |
Benign asbestos pleural diseases | p. 428 |
Malignant mesothelioma | p. 435 |
Spontaneous pneumothorax | p. 445 |
Non-spontaneous pneumothorax | p. 464 |
Pediatric pleural diseases | p. 475 |
Drainage and biopsy techniques | p. 481 |
Medical thoracoscopy | p. 498 |
Surgery of the pleural cavity | p. 513 |
Gene therapy in pleural diseases | p. 526 |
Future directions | p. 536 |
Index | p. 542 |
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