Oxford Textbook of Rheumatology

The new edition of this highly successful textbook is now available in one carefully integrated volume. A strong clinical emphasis is present throughout from the first section of commonly presenting problems through to the section addressing problems shared with a range of other clinical sub-specialties. The therapy of rheumatic diseases has undergone radical change in the last years with new biological therapies as the new evidence for therapies is covered extensively. In order to tackle the question of how these clinical problems arise a well-written beautifully illustrated account is given of fundamental processes of inflamation. This clearly shows that usculoskeletal diseases in the main arise as a combination of gentic, hormonal, environmental an other factors which conspire against the individual. The fourth section deals with the important topic of investigations. Patients with rheumatological disease often suffer a wide variety of complications and this section provides a detailed review of means of assessment. The book also provides a thorough and comprehensive review of the many forms of arthritis and their allied complications, illustrated by many colour photographs. Clinical algorithms are provided throughout to facilitate discussions about management in each of the major forms of arthritis.

1.1. Clinical presentation of rheumatic disease1.1.1. The adult patient, Anthony Russell1.1.2. The child, Ross E. Petty1.1.3. Adolescence and transition, Janet McDonagh & Russell Viner1.1.4. The geriatric age group, Evan Calkins1.1.5. Principles of examination, Peter van Riel1.1.6. Psychological aspects of rheumatic disease, Stanton Newman1.1.7. Growth and skeletal maturation, Alberto Martini, Mohamed Maghnie & Fabrizio Benedetti1.2. Common clinical problems1.2..1.1. Spinal problems in adults, Andrew O. Frank1.2.1.2. Spinal problems in children, Berit Flato, Roger Sorensen & Oystein Forre1.2.2. Regional problems1.2.2.1. The upper limbs in adults, Adel G. Fam & Simon Carette1.2.2.2. The lower limbs in adults, Robert W. Simms1.2.2.3. The arm and leg in children, Angelo Ravelli1.2.3. Extra-articlular features of rheumatic diseases, I.D.Griffiths1.3. Views from different perspectives1.3.1. Pregnancy and lactation1.3.1.1. Pregnancy, J.M.W.Hazes1.3.1.1.2. Antirheumatic drugs in pregnancy & lactation, J.M.W.Hazes1.3.2. The skin and rheumatic disease, C.R.Lovell1.3.3. Neurological complications, Iain T Ferguson & Peter Hollingworth1.3.4. The cardiovascular system, Susan Manzi & Mary Chester Wasko1.3.5. The respiratory system, Stephen G Spiro & David A Isenberg1.3.6. The gastrointestinal tract, Erkki Eerola, Reijo Peltonen & Timo Mottonen1.3.7. Liver, spleen and pancreas, Daniel Fishman1.3.8. The endocrine system, Jiri Vencovsky & Peter Broulik1.3.9. Oncology, Deborah P M Symmons1.2.10. Haematology, Alexander Kai-Lik So1.3.11. An anaesthetic perspective, Allan I Binder & Frances Dormon1.2.12. The eye, Elizabeth M Graham & Alison M Leak1.3.13. The kidney, Carolyn P Cacho, Andrew O'Connor & Gary M Kammer1.3.14. Psychiatric issues in rheumatology, Sikon M Helfgott & Malcolm P Rogers2. Outcomes and Issues in Delivering Rheumatological Care2.1. Outcome assessment in rheumatology, Thomas Stoll & Gerold Stucki2.2. Rehabilitation of adults, Richard Haigh2.3. Rehabilitation of children, Renate Hafner & Marianne Spamer2.4. Rheumatic disease and sexuality, David Siegel & John Baum2.5. Health cost economics and rheumatology, Ann Clarke, John Penrod & Bruno Fautrel3. Pathophysiology of Musculoskeletal Disease3.1. Genomics and its relevance to rheumatology, Patricia Woo & David Glass3.2. Molecular abnormalities of collagen and connective tissue, Michael Pope3.3. Articular cartilage, T E Hardingham3.4. Bone in health and disease, Roger Smith3.5. The physiology of the joint and its disturbance in inflammation, David Blake, Paul Mapp & Cliff R Stevens3.6. Synovial pathology, Barry Bresnihan3.7. Skeletal muscle physiology and damage, Joan M Round & D A Jones3.8. Biomechanics of articulations and derangements in disease, Anthony Unsworth, Susan Scholes, Andrew Amis & Anthony Bull4 The Process of INflammation. 4.1. Cells, cytokines and chemokines, Kevin Davies & Patricia Woo4.2. Leukocyte trafficking in inflammation, Dorian O Haskard4.3. Specific immune responses, B P Wordsworth & Frances Hall4.4. Animal models of arthritis, Wim van den Berg4.5. Modification of Inflammation4.5.1. Non-steroidal anti-inflammatory drugs - old and new, Kay Brune & Burkhard Hinz4.5.2. The place of corticosteroids in the management of rheumatic disease, John Kirwan4.5.3. Immunosuppressive and other drugs - monotherapy vs combination therapy, Ferdinand C Breedveld & Edward Keystone4.5.4. The future targets, Gabriel S Panayi5. Investigation of the Rheumatic Diseases5.1. ACute phase response, Douglas Thompson & Howard A Bird5.2. Biochemistry, Douglas Thompson & Howard A Bird5.3. Microbiology and diagnostic serology, Geoff M Scott5.4. Immunology laboratory tests, Peter Maddison & Pearl Huey5.5. Joint fluid, Lawrence Houk5.6. Imaging5.6.1. Imaging in adults, Peter Renton & P Conaghan5.6.2. Imaging in children, G H Sebag & T Laor5.7. Histopathology, Patrick J Gallagher & ? Anderson5.8. Electrophysiology, Adam Young6. The Scope of Rheumatic Disease6.1. Epidemiology6.1.1. Epidemiology and the rheumatic diseases, Cyrus Cooper & Karen Walker-Bone6.1.2. Epidemiology of rheumatic diseases in selected non-European populations, Patricia A Fraser6.2. Infections6.2.1. Pyogenic arthritis in adults, Marc L Miller6.2.2. Pyogenic arthritis in children, Douglas Swanson & Mary Anne Jackson6.2.3. Osteomyelitis and associated conditions, Emilio Bouza, P Munoz, Girish Desai, Yakub Mulla6.2.4. Lyme disease, Gerd-Rudiger Burmeister & Andreas Krause6.2.5. Viral arthritis, Stanley J Naides6.2.6. HIV infection, Patrick Venables6.2.7. Myobacterial diseases, Sanjiv N Amin6.2.8. Brucellar arthritis, Eliseo Pascual6.2.9. Parasitic involvement, Yusuf I Patel6.2.10. Fungal arthritis, Carol A Kemper & Stanley C Deresinski6.2.11. Immunodeficiency, A D B Webster6.2.12. Rheumatic fever, Allan Gibofsky & John B Zabriskie6.3. Rheumatic arthritis6.3.1. Immunopathogenesis of rheumatoid arthritis, R N Maini & M Feldmann6.3.2. Rheumatoid arthritis - the clinical picture, Leo van de Putte6.3.3. Rheumatoid arthritis - management, Paul Emery6.3.4. Polyarticular rheumatoid factor positive (seropositive) juvenile idiopathic arthritis, Alberto Martini6.4. Rheumatic arthritis6.4.1. Spondylarthropathy, undifferentiated spondylarthritis and overlap, Eric Veys & Herman Mielants6.4.2. Spondylarthritis in childhood, W Kuis & Tauny Southwood6.4.3. Ankylosing spondylitis, Andrei Calin6.4.4. Psoriatic arthritis, Dafna D Gladman6.4.5. Reactive arthritis and enteropathic arthropathy, J S Hill Gaston6.5. Arthropathies primarily occurring in childhood6.5.1. Pauciarticular-onset juvenile chronic arthritis, David D Sherry, Elizabeth D Mellins, C Sandborg & Vivian E Saper6.5.2. Systemic-onset juvenile chronic arthritis, Rayfel Schneider & Ronal M LaxerCarol M Black & Christopher P Denton6.5.3. Rheumatoid factor-negative polyarthritis in children, Anne-Marie F Prieur6.6. Systemic lupus erythematosus6.6.1. Systemic lupus erythematosus in adults - clinical features and aetiopathogenesis, Michael Ehrenstein & David A Isenberg6.6.2. SLE - management in adults, David A Isenberg & Anisur Rahman6.6.3. Paediatric systemic lupus erythematosus, Earl D Silverman & Diane Hebert6.6.4. The antiphospholid antibody syndrome, Munther A Khamashta & G R V Hughes6.7. Scleroderma and related disorders in adults and children, Carol M Black & Christopher P Denton6.8. Polymyositis and dermamyositis6.8.1. Polymyositis and dermamyositis in adults, Ira N Targoff6.8.2. Polymyositis and dermamyositis in children, Lauren M Pachman6.9. Sjogren's syndrome, Arthanasios G Tzioufas, Pierre Youinou, Haralampos & Moutsopoulos6.10. Vasculitis6.10.1. Classification and epidemiology of vasculitis, David G I Scott & Richard A Watts6.10.2. Clinical features of primary ANCA-associated vasculitis, Wolfgang L Gross & Eva Reinhold-Keller6.10.3. Treatment of primary ANCA-associated vasculitis, DAvid Jayne & Niels Rasmussen6.10.4. Secondary vasculitis and vasculitis mimics, Richard A Watts & David G I Scott6.10.5. Large vessel vasculitis/gian cell arteritis, Elisabeth Nordberg6.10.6. Polymyaligia rheumatica, B Dasgupta & Shubada Kalke6.10.7. Other vasculitides including small vessel vasculitis, Miguel A Gonzalez-Gay & Carlos Garcia- Porrua6.10.8. Behcet's syndrome, Hasan Yazici6.10.9. Vasculitis in children, Ozen6.11. Overlap syndromes in adults and children, Enrique R Soriano & Neil J McHugh6.12. Miscellaneous inflammatory conditions6.12.1. Amyloidosis, P N Hawkins6.12.2. Familial Mediterranean fever, Pnina Langevitz, Avi Livneh, Deborah Zemer & Mordechai Pras6.12.3. Periodic fevers, Michale F McDermott6.12.4. Panniculitis, Jeffrey P Callen6.12.5. Neurtophilic dermatoses, Jeffrey P Callen6.12.6. Sarcoidosis, Barry Bresnihan6.12.7. Macrophage activation syndrome, Alexei Grom6.12.8. The chronic, infantile, neurological, cutaneous and articular syndrome, Anne-Marie F Prieur6.12.9. Multicentric reticulohistiocytosis, Peter J Maddison6.12.106.12.10. Hyperlipidaemias, Keng Hong Leong, J P D Reckless & Neil J McHugh6.13. Soft Tissue Rheumatism6.13.1. Fibromyalgia and diffuse pain syndromes - adult onset, Bijlsma, Hans Jacobs & R Geenan6.13.2. Local pain syndromes - adult onset, Michael Shipley6.13.3. Pain syndromes - childhood onset, Kevin Murray6.14. Osteoarthritis, Michael Doherty. Adrian Jones & T T Cawston6.15. Crystal arthropathies, Ann K Rosenthal6.16.1. Osteoporosis and osteomalacia, David M Reid6.16.2. Paget's disease of bone, S E Papapoulos6.16.3. Miscellaneous disorders of bone, cartilage and synovium, Peter J Maddison6.16.4. Diseases of bone and cartilage in children, Christine Hall & Patricia Woo6.17. Disorders of the spine6.17.1iNTEV6.17.1. Intevertebral disc disease and other mechanical disorders of the back, Malcolm I V Jayson6.17.2. Cervical pain syndromes, Allan I Binder6.18.1. Algodystrophy, Geoffrey O Littlejohn6.18.2. Rheumatic complications of drugs and toxins, Robert M Bernstein7. Surgical Intervention and Sports Medicine7.1. Surgery in adults, Justn P Cobb7.2. Surgery in children, Johann Delf Witt7.3. Corticosteroid injection therapy, Allan I Binder7.4. Sports medicine, Mark Harries7.5. Sports injuries, Shirley Emerson & J R Jenner