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9781555812973

The Pneumococcus

by ; ; ;
  • ISBN13:

    9781555812973

  • ISBN10:

    155581297X

  • Format: Hardcover
  • Copyright: 2004-06-01
  • Publisher: Amer Society for Microbiology

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Summary

The Pneumococcus is a state-of-the-art examination of recent research in this field and the impact of this gram-positive pathogen on human disease. Written by the foremost experts in the field including a foreword by Robert Austrian, the book integrates pneumococcal physiology, pathogenesis, and host-pathogen interactions. The Pneumococcus provides coverage of topics in basic microbiology such as details of DNA transformation, molecular and medical epidemiology, the molecular basis of invasive disease, and various interactions with host defenses.

Table of Contents

Contributors ix
Foreword xv
Robert Austrian
Preface xxix
THE BACTERIA
1(116)
Genome
What Is a Pneumococcus?
3(12)
Christopher G. Dowson
Comparative Genomics of Streptococcus pneumoniae: Intrastrain Diversity and Genome Plasticity
15(15)
Herve Tettelin
Susan K. Hollingshead
Surface Anatomy
Capsules
30(19)
Janet Yother
Choline-Binding Proteins
49(12)
Edwin Swiatlo
Larry S. McDaniel
David E. Briles
Pneumolysin and Other Virulence Proteins
61(14)
Tim J. Mitchell
Microbial Physiology
Cell Wall Hydrolases
75(14)
Rubens Lopez
Ernesto Garcia
Pedro Garcia
Jose Luis Garcia
Transformation
89(28)
Sanford A. Lacks
HOST-MICROBE INTERACTIONS
117(164)
Exposure and Colonization
Evolutionary and Population Biology of Streptococcus pneumoniae
119(17)
Brian G. Spratt
William P. Hanage
Angela B. Brueggemann
Pneumococcal Carriage
136(12)
Derrick W. Crook
Angela B. Brueggemann
Karen L. Sleeman
Timothy E. A. Peto
Epidemiology of Pneumococcal Disease
148(21)
Jay C. Butler
Mechanisms of Carriage
169(14)
Jeffrey N. Weiser
Invasion and Infection
Inflammation and Host Defense
183(18)
Paul Anthony Majcherczyk
Philippe Moreillon
Interactions of Streptococcus pneumoniae with the Proteins of the Complement Pathways
201(10)
Margaret K. Hostetter
A Pathogenetic Categorization of Clinical Syndromes Caused by Streptococcus pneumoniae
211(10)
Daniel M. Musher
Attachment and Invasion of the Respiratory Tract
221(17)
Elaine I. Tuomanen
Pathogenesis of Pneumococcal Meningitis
238(14)
Joerg R. Weber
Immunodeficiency and Invasive Pneumococcal Disease
252(29)
Edward N. Janoff
Jeffrey B. Rubins
TREATMENT AND PREVENTION
281(140)
Changing the Ecology of Pneumococci with Antibiotics and Vaccines
283(31)
Ron Dagan
Marc Lipsitch
Pneumococcal Infections: Therapeutic Strategies and Pitfalls
314(17)
Kathryn M. Edwards
Clinical Relevance of Antibiotic Resistance in Pneumococcal Infections
331(8)
Keith P. Klugman
Mechanisms for Penicillin Resistance in Streptococcus pneumoniae: Penicillin-Binding Proteins, Gene Transfer, and Cell Wall Metabolism
339(11)
Carina Bergmann
Fang Chi
Shwan Rachid
Regine Hakenbeck
Macrolide, Quinolone, and Other Non-β-Lactam Antibiotic Resistance in Streptococcus pneumoniae
350(17)
Karita Ambrose
David S. Stephens
The Humoral Immune Response to Streptococcus pneumoniae
367(15)
Clifford M. Snapper
Jesus Colino
Abdul Q. Khan
Zheng Qi Wu
New Pneumococcal Vaccines: Basic Science Developments
382(21)
James C. Paton
Vaccine-Induced Immunity to Pneumococcal Infection
403(18)
P. Helena Makela
Helena Kayhty
Index 421

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