Textbook of Biochemistry with Clinical Correlations, 5th Edition

by Thomas M. Devlin (Hahnemann School of Medicine, Philadelphia, Pennsylvania)

• ISBN13: 9780471411369
• ISBN10: 0471411361
• Edition: 5th
• Format: Hardcover
• Copyright: 2002-01-01
• Publisher: Wiley-Liss

Summary

This newly revised and updated fifth edition of Devlin's Textbook of Biochemistry with Clinical Correlations presents the biochemistry of mammalian cells, relates events at the cellular level to physiological processes in the whole animal, and cites examples of human diseases derived from aberrant biochemical processes. This edition significantly expands the clinical correlation that highlight the significance of biochemistry to specific clinical problems. Full-color illustrations provide clear explanations for the concepts discussed, and end-of-chapter questions and answers act as challenging study material. Reorganized into five practical sections, Textbook of Biochemistry with Clinical Correlations covers these topics and much more: Structure of macromolecules-DNA, RNA, and protein structure Information transmission-replication, transcription, protein synthesis, and control of gene expression Functions of proteins-protein families, enzymes, membrane structure, and transport mechanisms Metabolic pathways and their control-carbohydrate, lipid, amino acid, and nucleotide metabolism Physiological processes-hormone and signal transduction, biochemistry of nervous tissue, muscle vision, coagulation and digestion, and principles of nutrition

Table of Contents

PART I: STRUCTURE OF MACROMOLECULES.

1. Eukaryotic Cell Structure (T.M. Devlin).

2. DNA and RNA: Composition and Structure (S.A. Woski and F.J. Schmidt).

3. Proteins I: Composition and Structure (R.M. Schultz and M.N. Liebman).

PART II: TRANSMISSION OF INFORMATION.

4. DNA Replication, Recombination, and Repair (H.J. Edenberg).

5. RNA: Transcription and RNA Processing (F.J. Schmidt).

6. Protein Synthesis; Translation and Posttranslational Modifications (D. Glitz).

7. Recombinant DNA and Biotechnology (G. Soslau).

8. Regulation of Gene Expression (D.L. Weeks and J.E. Donelson).

PART III: FUNCTIONS OF PROTEINS.

9. Proteins II: Structure-Function Relationships in Protein Families (R.M. Schultz and M.N. Liebman).

10. Enzymes: Classification, Kinetics, and Control (J.L. York).

11. The Cytochromes P450 and Nitric Oxide Synthases R.T. Okita and B.S.S. Masters).

12. Biological Membranes: Structure and Membrane Transport (T.M. Devlin).

PART IV: METABOLIC PATHWAYS AND THEIR CONTROL.

13. Bioenergetics and Oxidative Metabolism (D.S. Beattie).

14. Carbohydrate Metabolism I: Major Metabolic Pathways and Their Control (R.A. Harris).

15. Carbohydrate Metabolism II: Special Pathways and Glycoconjugates (N.B. Schwartz).

16. Lipid Metabolism I: Utilization and Storage of Energy in Lipid Form (J.D. McGarry).

17. Lipid Metabolism II: Pathways of Metabolism of Special Lipids (R.H. Glew).

18. Amino Acid Metabolism (M.W. Coomes).

19. Purine and Pyrimidine Nucleotide Metabolism (J.G. Cory).

20. Metabolic Interrelationships (R.A. Harris and D.W. Crabb).

PART V: PHYSIOLOGICAL PROCESSES.

21. Biochemistry of Hormones I: Polypeptide Hormones (G. litwach and T.J. Schmidt).

22. Biochemistry of Hormones II: Steroid Hormones (G. Litwack and T.J. Schmidt).

23. Molecular Cell Biology (T.E. Smith).

24. Iron and Heme Metabolism (W.M. Awad, jr.).

25. Digestion and Absorption of Nutritional Constituents (U. Hopfer).

26. Principles of Nutrition I: Macronutrients (S.G. Chaney).

27. Principles of Nutrition II: Micronutrients (S.G. Chaney).

Review of Organic Chemistry (C.N. Angstadt).

Appendix.

Index